Demand for non-invasive treatments have boomed in the last decade. Nearly 70% of consumers considered getting cosmetic procedures and interest in injections show no signs of slowing down. As popular as these treatments may be, there is a downside to getting injectable treatments too often. Products like botulinum (Botox) and fillers like Restylane create instant results, freezing out wrinkles and plumping up lips and lines. You can develop resistance to these products over time, which can reduce their effectiveness and the duration of the effects.

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When you use a filler or injectable, you’ll see almost instant results; those results are temporary, though. The amount of time the results last will depend on y our body chemistry, the product used and even the location. While you are more likely to build up a resistance to Botox, it can happen with fillers as well. With Botox, you’ll find that you need higher doses or that you need to up the frequency of the treatments; switching to a different brand like Xeomin or Dysport can also help.

For fillers, the brand you choose may make a difference, according to Allure magazine. Different products last for variable amounts of time, since they have varying ingredients and density. Your dermatologist can give you an idea of how long your filler should last and how frequently you’ll need to come back. Your own metabolism plays a role as well; some people just burn through and absorb fillers faster than others.

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Since fillers need to be regularly updated, there is a risk of resistance; it won’t harm you physically, but it will impact your schedule and your pocketbook. When you develop a resistance to a filler, it simply won’t last as long or be as effective. Your dermatologist can help you by switching up brands, but once your body adapts to and begins to efficiently metabolize fillers injected under your skin, you’ll simply have to get them more often.

The best way to avoid this situation is to stretch the time out between injections and get fillers in the most needed areas first. Every injection you get increases your body’s ability to metabolize the ingredients, so if you overload on your first visit, you may find your filler doesn’t last as long as expected.

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Switching brands and talking to your dermatologist about the best ways to prolong filler life and the ideal schedule to enhance your appearance without developing resistance is the best way to ensure you get the most from the process. Simply knowing that resistance is possible can help you take steps to avoid it and to ensure you keep that fresh, youthful look as long as possible.